Pure Age Defiance Serum

Softens the Appearance of Expression Lines
12% SNAP-8 Peptide is designed to help reduce the visible appearance of expression wrinkles, particularly those associated with repetitive facial movements.

Intensive Hydration & Plumping
Hyaluronic Acid attracts and retains water, helping temporarily plump dehydration lines and leave skin feeling softer and more supple.

Supports Firmness & Elasticity
Peptides, vitamins and antioxidants help support skin resilience and a smoother, firmer-looking complexion.

Brightens Dull Skin
A multi-vitamin complex and Niacinamide help improve the appearance of dullness and uneven tone.

Antioxidant Protection
Helps protect against oxidative stress and environmental factors that contribute to premature skin ageing.

Supports the Skin Barrier
Niacinamide and essential skin-supporting nutrients help maintain moisture retention and healthy barrier function.

SNAP-8 Peptide 12% (Acetyl Octapeptide-3)
A peptide designed to target the appearance of expression wrinkles. It works through a cosmetic signalling mechanism associated with facial muscle contractions, helping soften the look of lines with consistent use. Unlike cosmetic injectables, it does not immobilise muscles.

Hyaluronic Acid (Sodium Hyaluronate)
A moisture-binding ingredient that attracts and retains water, helping improve hydration, suppleness and the appearance of fine dehydration lines.

Multi-Vitamin Complex
A combination of skin-supporting vitamins and nutrients that help maintain healthy skin function, antioxidant protection and overall resilience.

Niacinamide (Vitamin B3)
Supports the skin barrier, helps maintain moisture retention and improves the appearance of redness, uneven tone and dullness.

Proteolea®
An antioxidant and anti-glycation complex designed to help protect skin proteins against environmental and oxidative stress associated with visible ageing.

• Fine lines and expression wrinkles

• Dehydrated skin

• Early signs of ageing

• Mature skin

• Skin lacking firmness or suppleness

• Dull or tired-looking skin

• Those wanting a lightweight anti-ageing serum

• Anyone looking to support smoother skin without strong exfoliating actives

• Those wanting a topical approach to expression lines

Apply ½–1 pump morning and/or evening to freshly cleansed skin.

Gently massage over the face and neck, including around the eye area, avoiding direct contact with the eyes.

Follow with your moisturiser and SPF in the morning.

Can be layered with other corrective serums depending on your skin concerns and routine.

Serums are designed to deliver concentrated active ingredients to the skin to target specific concerns. While your cleanser and moisturiser support the overall health and function of your skin, a serum can add a more targeted step to your routine.

Depending on the ingredients, serums can help address concerns such as dehydration, pigmentation, breakouts, redness, oiliness and visible signs of ageing. They can also support the skin barrier and provide antioxidant protection.

Because serums are usually lightweight and formulated with a higher concentration of specific active ingredients, they can be an effective way to personalise your skincare routine around what your skin needs.

You don't necessarily need lots of serums either. The right one or two, chosen for your skin and concerns, can make a meaningful difference as part of a consistent routine.

Think of your serum as the targeted treatment step in your skincare routine — chosen to support your specific skin goals.

Professional Australian-made skincare focused on skin health, corrective care and long-term skin function.

O COSMEDICS combines skin science with functional active ingredients to create high-performance skincare designed to address a wide range of skin concerns while supporting the health of the skin barrier.

Skin First Philosophy

O COSMEDICS follows the principles of Corneotherapy, a skin treatment philosophy centred around protecting, repairing and maintaining the skin's outermost layer — the stratum corneum.

Rather than taking an aggressive approach to skincare, the range focuses on working with the skin's natural biology and supporting healthy skin function. Active ingredients and corrective treatments can then be introduced according to what the skin needs and can tolerate.

Functional Actives

O COSMEDICS products are formulated with functional doses of active ingredients selected for their ability to support specific skin functions and concerns.

These actives are used across the range to target concerns including pigmentation, acne, congestion, dehydration, inflammation, redness, loss of firmness and visible signs of ageing.

Science & Skin Health

O COSMEDICS takes a skin-health approach that considers more than just the visible appearance of the skin.

Its formulations are designed around key factors that influence skin ageing and function, including collagen breakdown, inflammation, glycation, photo damage and oxidation.

The range also incorporates biomimetic ingredients — ingredients designed to work in harmony with the skin's natural structure and processes — alongside O COSMEDICS' V8 Peptide Complex®.

Australian Made & Woman Owned

O COSMEDICS is proudly Australian made, with its products manufactured at its Sydney-based facility.

The brand was developed in Australia with the unique skin challenges of the Australian environment and climate in mind. O COSMEDICS was founded by Australian skin and beauty therapist Maria Enna-Cocciolone.

Professional Skincare

O COSMEDICS is used by professional skin therapists and clinics in Australia and internationally.

The range includes everyday skincare as well as more targeted corrective products, allowing routines to be tailored to different skin types, concerns and stages of skin health.

The goal is simple: support healthy skin, address individual concerns and achieve visible results without losing sight of the skin's long-term health.

• Free from parabens, sulfates, petrochemicals and mineral oils

• Free from artificial colours and harsh preservatives

• Free from harsh synthetic fragrances

• Vegan-friendly, gluten-free and cruelty-free

• Emulsifier-free

• Formulated with biomimetic ingredients designed to work in harmony with the skin's natural physiology

Aqua, Sodium Hyaluronate, Acetyl Octapeptide-3, Retinyl Palmitate, Thermus Thermophilus Ferment, Biotin, Inositol, Niacinamide, Tocopherol, Linoleic Acid, Calcium Pantothenate, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Caprylyl Glycol, Phenoxyethanol.