Potent Retinol Serum 0.5%

Refines Skin Texture
Retinol supports healthy cell turnover, helping smooth rough, thickened or uneven-looking skin.

Helps With Congestion & Breakouts
Supports clearer pores and helps regulate excess oil, making it particularly useful for oily, congested and breakout-prone skin.

Supports Collagen & Firmness
Retinol and peptides support collagen and elasticity, helping improve the appearance of fine lines and visible signs of ageing.

Helps Improve Pigmentation
Supports skin renewal to help improve the appearance of dark spots, uneven tone and mild sun damage.

Balances Excess Oil
Helps regulate oil production and reduce excess shine while supporting clearer-looking skin.

Progressive Retinol Delivery
The Retinol is encapsulated for a gradual, controlled release into the skin.

Encapsulated Retinol 0.5%
A form of Vitamin A that supports cell turnover, collagen production, clearer pores and more even skin tone and texture.

Niacinamide (Vitamin B3)
Helps support the skin barrier, regulate oil and improve the appearance of uneven tone.

Vitamin E
Provides antioxidant support while helping maintain moisture and barrier function.

SymRelief®
A soothing complex that helps calm and reduce the appearance of irritation and redness.

V8 Peptide Complex® + Peptides
Supports collagen, elasticity and overall skin function.

• • Oily skin

  • Congestion and blocked pores

  • Mild breakouts

  • Rough or uneven texture

  • Excess oil and shine

  • Fine lines and visible signs of ageing

  • Pigmentation and uneven tone

  • Mild sun damage

Start by using every second to third evening.

Mix ½–1 pump into your O COSMEDICS Hydrator and apply over the face, avoiding the eye area.

As your skin adjusts, gradually increase to every second evening and eventually nightly if appropriate for your skin.

O COSMEDICS advises not applying this serum neat to the entire face. It may be applied neat when specifically spot-treating areas of dark pigmentation.

Always wear SPF during the day.

• Do NOT use if pregnant or breastfeeding

• Avoid the eye area

• If skin feels itchy, stinging and appears red and inflamed (retinoid response) stop using until this has resolved and slowly reintroduce

• If this occurs again, you may have the incorrect form of Vitamin A for your skin, opt for Retinoic Oil or Retinal V8 Fusion and always consult an O Skin Expert

• It is normal to feel dry when first beginning on Retinol however, red, burning and stinging is not necessary and is a sign you’ve either used too much too fast, or your skin needs a different form of Vitamin A

Serums are designed to deliver concentrated active ingredients to the skin to target specific concerns. While your cleanser and moisturiser support the overall health and function of your skin, a serum can add a more targeted step to your routine.

Depending on the ingredients, serums can help address concerns such as dehydration, pigmentation, breakouts, redness, oiliness and visible signs of ageing. They can also support the skin barrier and provide antioxidant protection.

Because serums are usually lightweight and formulated with a higher concentration of specific active ingredients, they can be an effective way to personalise your skincare routine around what your skin needs.

You don't necessarily need lots of serums either. The right one or two, chosen for your skin and concerns, can make a meaningful difference as part of a consistent routine.

Think of your serum as the targeted treatment step in your skincare routine — chosen to support your specific skin goals.

Professional Australian-made skincare focused on skin health, corrective care and long-term skin function.

O COSMEDICS combines skin science with functional active ingredients to create high-performance skincare designed to address a wide range of skin concerns while supporting the health of the skin barrier.

Skin First Philosophy

O COSMEDICS follows the principles of Corneotherapy, a skin treatment philosophy centred around protecting, repairing and maintaining the skin's outermost layer — the stratum corneum.

Rather than taking an aggressive approach to skincare, the range focuses on working with the skin's natural biology and supporting healthy skin function. Active ingredients and corrective treatments can then be introduced according to what the skin needs and can tolerate.

Functional Actives

O COSMEDICS products are formulated with functional doses of active ingredients selected for their ability to support specific skin functions and concerns.

These actives are used across the range to target concerns including pigmentation, acne, congestion, dehydration, inflammation, redness, loss of firmness and visible signs of ageing.

Science & Skin Health

O COSMEDICS takes a skin-health approach that considers more than just the visible appearance of the skin.

Its formulations are designed around key factors that influence skin ageing and function, including collagen breakdown, inflammation, glycation, photo damage and oxidation.

The range also incorporates biomimetic ingredients — ingredients designed to work in harmony with the skin's natural structure and processes — alongside O COSMEDICS' V8 Peptide Complex®.

Australian Made & Woman Owned

O COSMEDICS is proudly Australian made, with its products manufactured at its Sydney-based facility.

The brand was developed in Australia with the unique skin challenges of the Australian environment and climate in mind. O COSMEDICS was founded by Australian skin and beauty therapist Maria Enna-Cocciolone.

Professional Skincare

O COSMEDICS is used by professional skin therapists and clinics in Australia and internationally.

The range includes everyday skincare as well as more targeted corrective products, allowing routines to be tailored to different skin types, concerns and stages of skin health.

The goal is simple: support healthy skin, address individual concerns and achieve visible results without losing sight of the skin's long-term health.

• Free from parabens, sulfates, petrochemicals and mineral oils

• Free from artificial colours and harsh preservatives

• Free from harsh synthetic fragrances

• Vegan-friendly, gluten-free and cruelty-free

• Emulsifier-free

• Formulated with biomimetic ingredients designed to work in harmony with the skin's natural physiology

Aqua, Cyclopentasiloxane, Dimethicone Crosspolymer, Cyclohexasiloxane, Peg/ppg-18/18 Dimethicone, Caprylic/Capric Triglyceride, Retinol, Tocopheryl Acetate, Glycerin, Acetyl Octapeptide-3, Thermus Thermophilus Ferment, Niacinamide, Zingiber Officinale (Ginger) Root Extract, Bisabolol, Polymethyl Methacrylate, Bht, Tricaprylin, Phenoxyethanol, Caprylyl Glycol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80.